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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Rabbit polyclonal antibody to human KCNN4 (11-28): Affinity purified/R-1068-100/100 µg
产品编号:R-1068-100
市  场 价:¥6540.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$327.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Rabbit polyclonal antibody to human KCNN4 (11-28): Affinity purified/R-1068-100/100 µg
商品介绍
Description
KCNN4isamulti-passmembraneproteinandbelongstothepotassiumchannelKCNNfamily.KCNN4formsavoltage-independentpotassiumchannelthatisactivatedbyintracellularcalcium.ThechannelisblockedbyclotrimazoleandcharyBDotoxin.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenAsyntheticpeptidecorrespondingtoaregion(11-28)fromhumanKCNN4.Toenhancetheimmunologicalresponse,thispeptidewascoupledtocarrierproteinBSA.
OtherNamesSK4;KCa4;IKCa1;IK1;PutativeGardoschannel;KCNN4;IK1;IKCA1;KCA4;SK4;KCA3.1;Intermediateconductancecalcium-activatedpotassiumchannelprotein4;
AccessionO15554KCNN4_HUMAN;
ProducedinRabbit
PurityAffinitypurifiedonantigencolumn
ApplicationsWesternBlotting(WB).Aconcentrationof0.1-0.5µg/mlisrecommendedforWB.HumanKCNN4hasapredictedlengthof427residuesandMWof48kDa.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBagainsttheantigen.
Cross-reactivityHuman;rat;predictedtoreactwithmouseduetosequencehomology;
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilisedwith5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3
ReconstitutionReconstitutein100µlofsteriledistilledwatertoachieveanantibodyconcentrationof1mg/ml.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles
ExpiryDate12monthsafterpurchase
SpecificReferences1.RuggieriPetal(2012)TheinhibitionofKCa3.1channelsactivityreducescellmotilityinglioblastomaderivedcancerstemcells.PLoSOne.2012;7(10):e47825.
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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