Description | Theantibodyismadeagainstthemembrane-boundisoform1ofNeuropilin-1.Itisareceptorinvolvedinthedevelopmentofthecardiovascularsysterm,inangiogenesis,intheformationofcertainneuronalcircuitsandinorganogenesisoutsidethenervoussystem.Itbindsbothvascularendothelialgrowthfactor(VEGF)andsemaphorinfamilymembers.Isoform1isexpressedbybloodvesselsofdifferenttissues.Inthedevelopingembryoitispredominantlyfoundinthenervoussystem.Inadulttissues,itishighlyexpressedinheartandplacenta,moderatelyexpressedinlung,liverandskeletalmuscle,kidneyandpancreas,andlowinadultbrain. |
BatchNo. | Seeproductlabel |
Unitsize | 100µg |
Antigen | PartialrecombinanthumanNeuropilin-1(22-131)withaGSTtag. |
Isotype | IgG2aKappa |
Clone | 1B3 |
OtherNames | Vascularendothelialcellgrowthfactor165receptor;CD304antigen;NRP1;NRP;VEGF165R |
Accession | NRP1_HUMAN |
Producedin | Mouse |
Purity | ProteinGpurifiedimmunoglobulin |
Applications | ThisantibodyisrecommendedforWB,andsandwichELISA.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | SpecificityhasbeenconfirmedbyWBanddirectELISAagainsttheantigen. |
Cross-reactivity | Human.Otherspecieshavenotbeentested. |
Blastit | Toseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit. |
Form | LyophilisedfromPBSpH7.4 |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforhigherstABIlityorat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | 12monthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。