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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Chicken polyclonal antibody to Neurofilament Heavy phosphorylated/C-1386-50/50 µl
产品编号:C-1386-50
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Chicken polyclonal antibody to Neurofilament Heavy phosphorylated/C-1386-50/50 µl
商品介绍
DescriptionNeurofilamentscontainthreeintermediatefilamentproteins:light(68kDa),medium(160kDa)andheavy(200kDa).Neurofilamentheavy(NF200orNF-H)isphosphorylatedanditisthoughtthatthisresultsintheformationofinterfilamentcrossbridgesthatareimportantinthemaintenanceofaxonalcaliber.ThisantibodybindsprimarilytothephosphorylatedaxonalformsofNF-H.
BatchNo.Seeproductlabel
Unitsize50µl
AntigenPurifiedbovineNeurofilamentHeavy(NF-H)
IsotypeIgY
OtherNamesNF-200;NF200;NF-H;NEFH;N52;Neurofilamentheavypolypeptide;NeurofilamenttripletHprotein;200kDaneurofilamentprotein;KIAA0845;NFH;
AccessionP12036NFH_HUMAN;
ProducedinChicken
ApplicationsWesternBlotting(WB),Immunocytochemistry(IC)andELISA.SuggesteddilutionforWBis1:100,000-1,000,000.SuggesteddilutionforICis1:50,000-100,000.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThisantibodyreactswithphosphorylatedNF-Handisseenasabandofapprox200kDainWB.RefertopublicationbyShawetal(2005)fortheuseofthisantibodyinanELISAtodetectNF-H.
AntibodyAgainstNeurofilamentHeavyphosphorylated
Cross-reactivityHu,Rat,Ms,Fel,Chk.Predictedtoreactwithothermammaliantissuesduetosequencehomology.
BlastURLClickhere
FormLyophilisedwith5%trehalose
AppearanceWhitepowder
ReconstitutionReconstituteinsteriledistilledwater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionoflyophilisedantibody,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
SpecificReferences1.JarjourA.A.etal(2007)Maintenanceofaxo-oligodendroglialparanodaljunctionsrequiresDCCandnetrin-1.JNeurosci.2008Oct22;28(43):11003-14.
2.PearseD.D.etal(2007)TransplantationofSchwanncellsand/orolfactoryensheathinggliaintothecontusedspinalcord:Survival,migration,axonassociation,andfunctionalrecovery.Glia.2007Jul;55(9):976-1000.
3.ShawG.etal(2005)HyperphosphorylatedneurofilamentNF-HisaserumbioMarkerofaxonalinjury.BiochemBiophysResCommun.2005Nov4;336(4):1268-77.
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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