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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Mouse monoclonal antibody to human Bcl-2 (41-54) [BL-2]: IgG/M-968-100/100 µg
产品编号:M-968-100
市  场 价:¥6540.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$327.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Mouse monoclonal antibody to human Bcl-2 (41-54) [BL-2]: IgG/M-968-100/100 µg
商品介绍
DescriptionApoptosisregulatorBcl-2isanintegraloutermitochondrialmembraneproteinthatblockstheapoptoticdeathofsomecellssuchaslymphocytes.Atleast2isoforms(alphaandbeta)areproducedbyalternatesplicingwithdifferentC-terminalends.
BatchNo.Seeproductlabel.
Unitsize100µg
AntigenSyntheticpeptide(GAAPAPGIFSSQPG)correspondingtoaminoacids41-54fromhumanBcl-2conjugatedtothyroglobin.
CloneBL-2
OtherNamesBCL2;
AccessionP10415BCL2_HUMAN
ProducedinMouse
PurityIgG
ApplicationsImmunohistochemistry(IHC)andWesternBlotting(WB).Aconcentrationof1.0-2.0µg/mlisrecommendedforWB.HumanBcl-2hasapredictedlengthof239aaandMWof26kDa.Aconcentrationof0.4-1.0µg/mlisrecommendedtodetectBcl-2informalinfixedandparaffinembeddedtissuesaswellasformalin/acetonefrozentissues.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen.HumanbreastcancercelllineMCF-7,Helacells,normalandreactivelymphoidtissueswereusedtotestthespecificityofthisantibody.
Cross-reactivityHuman;Rat;
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilizedfrom1.2%sodiumacetate,2mgBSA,0.01mgNaN3
ReconstitutionReconstitutein1mlofPBS(pH7.4)toachieveanantibodyconcentrationof100µg/ml.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase.
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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